![]() ![]() ![]() Though difficult to discriminate dementia in its early stages from normal cognitive ageing, there is evidence from large cohort studies that, in general, those who developed dementia after follow-up exhibited poorer cognitive performance compared to those who did not develop the disease, although differences have been insufficient to translate into accurate individual risk prediction. ĭementia for most has a long prodromal period, whereby individuals who go onto develop dementia, exhibit cognitive deficits many years before any symptoms or receiving a clinical diagnosis. Arguments against screening highlight these uncertainties, including unnecessary investigation and treatment with no evidence of any benefit for the individual. This is due to uncertainty of clinical outcomes and effective interventions, with insufficient evidence of benefits over the harms of screening for cognitive impairment and dementia. Although early diagnosis of dementia is recommended in individuals displaying symptoms of the condition, current policies do not support screening or risk prediction at an individual level among apparently healthy individuals. For the purpose of primary prevention, we need a better understanding of the natural progression of the disease to allow targeting of specific risk factors to potentially modify early biological changes that may be an indication of future dementia. There has been an increased interest in the prevention or delay of the onset of dementia and of the early identification of individuals who are at high risk. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |